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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK15
All Species:
11.82
Human Site:
S259
Identified Species:
26
UniProt:
Q8TD08
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TD08
NP_620590.2
544
59832
S259
S
V
L
H
Q
L
G
S
R
P
R
Q
T
L
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539201
559
60934
A260
S
I
L
P
C
L
G
A
R
P
R
H
T
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y86
549
60660
S260
L
I
L
Q
N
L
G
S
R
P
Q
Q
T
L
D
Rat
Rattus norvegicus
Q9Z2A6
547
60705
S260
L
I
L
Q
N
L
G
S
R
P
R
Q
T
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423954
600
66936
S284
S
I
I
D
H
M
S
S
R
Q
R
V
T
L
E
Frog
Xenopus laevis
P26696
361
41238
T113
I
V
Q
D
L
M
E
T
D
L
Y
K
L
L
K
Zebra Danio
Brachydanio rerio
NP_001018581
524
58806
L260
S
V
I
Q
R
M
L
L
R
P
Q
V
P
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392445
747
85295
N271
N
L
L
E
K
T
P
N
A
P
R
R
S
L
K
Nematode Worm
Caenorhab. elegans
Q11179
470
54020
P222
L
I
G
R
A
L
F
P
G
S
S
T
I
N
Q
Sea Urchin
Strong. purpuratus
XP_001203135
583
64666
L261
T
F
V
D
M
S
K
L
R
H
R
Q
S
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P14681
368
42674
V120
S
T
L
S
D
D
H
V
Q
Y
F
T
Y
Q
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
71.5
N.A.
69.2
68.7
N.A.
N.A.
45.3
28.6
48.3
N.A.
N.A.
34.6
42.6
44.9
Protein Similarity:
100
N.A.
N.A.
77.8
N.A.
75.5
75.1
N.A.
N.A.
60
42
64.8
N.A.
N.A.
50.5
61.2
62.6
P-Site Identity:
100
N.A.
N.A.
66.6
N.A.
66.6
73.3
N.A.
N.A.
40
13.3
40
N.A.
N.A.
26.6
6.6
20
P-Site Similarity:
100
N.A.
N.A.
80
N.A.
80
80
N.A.
N.A.
66.6
33.3
66.6
N.A.
N.A.
66.6
13.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
10
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
28
10
10
0
0
10
0
0
0
0
0
46
% D
% Glu:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
19
% E
% Phe:
0
10
0
0
0
0
10
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
37
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
10
10
0
10
0
0
10
0
10
0
0
0
% H
% Ile:
10
46
19
0
0
0
0
0
0
0
0
0
10
10
10
% I
% Lys:
0
0
0
0
10
0
10
0
0
0
0
10
0
0
19
% K
% Leu:
28
10
55
0
10
46
10
19
0
10
0
0
10
73
0
% L
% Met:
0
0
0
0
10
28
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
19
0
0
10
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
10
0
0
10
10
0
55
0
0
10
0
0
% P
% Gln:
0
0
10
28
10
0
0
0
10
10
19
37
0
10
10
% Q
% Arg:
0
0
0
10
10
0
0
0
64
0
55
10
0
0
0
% R
% Ser:
46
0
0
10
0
10
10
37
0
10
10
0
19
0
0
% S
% Thr:
10
10
0
0
0
10
0
10
0
0
0
19
46
0
0
% T
% Val:
0
28
10
0
0
0
0
10
0
0
0
19
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
10
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _